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Recent publications (last 5 years):
Insect flight muscle
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Barton B, Ayer G, Heymann N, Maughan DW, Lehmann
F-O, Vigoreaux JO (2005) Flight muscle properties and aerodynamic
performance of Drosophila expressing a flightin transgene. J. Exp.
Biol. 208, 549-560.
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Dickinson M, Farman G, Frye M, Bekyarova T, Gore
D, Maughan D, Irving T (2005) Molecular dynamics of cyclically contracting
insect flight muscle in vivo. Nature 433, 330-333.
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Liu H, Miller MS, Swank DM, Kronert WS, Maughan
DW, Bernstein SI (2005) Paramyosin phosphorylation site disruption
affects indirect flight muscle stiffness and power generation in
Drosophila melanogaster. PNAS 102(30), 10522-10525.
Maughan D, Vigoreaux J. (2005) Nature’s strategy
for optimizing power generation in insect flight muscle, in: Sliding
filament mechanism in muscle contraction: Fifty years of research,
ed. H. Sugi, Ad. Exp. Med. Biol. 565, 157-167.
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Maughan D, Swank D (2005) Insect flight muscle chemomechanics,
in: Nature’s Versatile Engine: Insect Flight Muscle Inside
and Out, ed. J. Vigoreaux, Springer-Verlag, Boston, 251-269.
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Dickinson M, Farman G, Frye M, Bekyarova T, Gore
D, Maughan D, Irving T (2005) Molecular dynamics of cyclically contracting
insect flight muscle in vivo. Nature 433, 330-333.
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Henkin JA, Maughan DW, Vigoreaux JO (2004) Mutations
that affect flightin expression in Drosophila alter the viscolelastic
properties of flight muscle fibers. Am. J. Physiol. Cell Physiol.
286, C65-C72.
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Swank DM, Kronert WA, Bernstein SI, Maughan DW (2004)
Alternative N-terminal regions of Drosophila myosin heavy chain
tune muscle kinetics for optimal power output. Biophys. J. 87, 1805-1814.
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Henkin JA, Maughan DW, Vigoreaux JO (2003) Mutations
that affect flightin expression in Drosophila alter the viscolelastic
properties of flight muscle fibers. Am. J. Physiol. Cell Physiol.
286, C65-C72.
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Swank DM, Knowles AF, Suggs J, Sarsoza F, Lee A,
Maughan D, Bernstein S (2002) The myosin converter domain modulates
muscle performance. Nature Cell Biol. 4(4), 312-316. DOI: 10.1038/ncb/776.
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Irving T, Bhattacharya S, Tesic I, Moore J, Simcox
A, Vigoreaux J, Maughan D (2001) Changes in myofibrillar structure
and function produced by N-terminal deletion of the regulatory light
chain in Drosophila. J. Mus. Res. Cell Motil. 22(8), 675-683.
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Irving TC, Maughan DW (2001) Real-time X-ray studies
of living muscle. Ad. Photon Source Res. 4, 29-33.
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Irving T, Bhattacharya S, Tesic I, Moore J, Simcox
A, Vigoreaux J, Maughan D (2001) Changes in myofibrillar structure
and function produced by N-terminal deletion of the regulatory light
chain in Drosophila. J. Mus. Res. Cell Motil. 22(8), 675-683.
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Moore JR, Dickinson MH, Vigoreaux JO, Maughan DW
(2000) The effect of removing the N-terminal extension of the Drosophila
myosin regulatory light chain upon flight ability and the contractile
dynamics of indirect flight muscle. Biophys. J., 78(3), 1431-1440.
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Vigoreaux JO, Moore JR, Maughan DW (2000) Role of
the elastic protein projectin in stretch activation and work output
of Drosophila flight muscles. Elastic Filaments of the Cell, Ed.
Pollack G, Granzier H. Kluwer Academic/Plenum Publishers, 237-250.
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Nyland L, Maughan D (2000) Morphology and transverse
stiffness of Drosophila myofibrils measured by atomic force microscopy.
Biophys. J., 78(3), 1490-1497
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Irving TC, Maughan DW (2000) In vivo X-ray diffraction
of indirect flight muscle from Drosophila melanogaster, Biophys.
J. 78(5), 2511-2515
Vertebrate striated muscle
Human (heart research)
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Maughan D (2005) Kinetics and energetics of the
crossbridge cycle, in: Heart Failure Reviews, ed. M LeWinter, P
VanBuren. Heart Failure Reviews 10, 175-185.
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Fukagawa NK, Palmer BM, Barnes WD, Leavitt BJ, Ittleman
FP, LeWinter MM, Maughan DW (2005) Acto-myosin crossbridge kinetics
in humans with coronary artery disease: Influence of sex and diabetes
mellitus. J. Mol. Cell. Cardiol. 39(5), 743-753.
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Mulieri LA, Barnes W, Leavitt B, Ittleman F, LeWinter
M, Maughan D (2002) Alterations of myocardial dynamic stiffness
implicating abnormal cross-bridge function in human mitral regurgitation
heart failure. Circ. Res. 90(1), 66-72.
Rabbit (proteomics)
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Maughan DW, Henkin JA, Vigoreaux JO (2005) Concentrations
of glycolytic enzymes and other cytosolic proteins in the diffusible
fraction of a vertebrate muscle proteome. J. Cell. Mol. Proteomics
4, 1541-1549.
Rat (animal model of acquired disease)
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McCurdy DT, Palmer BM, Maughan DW, LeWinter MM (2001)
Myocardial cross-bridge kinetics in transition to failure in Dahl
salt-sensitive rats. Am J Physiol Heart Circ Physiol. 281(3), H1390-6
Mouse (animal model of inherited diseases)
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Miller MS, Palmer BM, Ruch S, Martin LA, Farman
GP, Wang Y, Robbins J, Irving RC, Maughan DW (2005) The essential
light chain N-terminal extension alters force and fiber kinetics
in mouse cardiac muscle. J. Biol. Chem. 280 (41), 34427-34434.
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Palmer BM, Georgakopoulos D, Jannsen PM, Wang Y,
Alpert NR, Belardi DF, Harris SP, Moss RL, Burgon PG, Seidman CE,
Seidman JG, Maughan DW, Kass DA (2004) Role of cardiac myosin binding
protein C in sustaining left ventricular systolic stiffening. Circ.
Res. 94, 1249-1255.
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Palmer BM, Fishbaugher DE, Schmitt JP, Wang Y, Alpert
NR, Seidman CE, Seidman JG, VanBuren P, Maughan DW (2004) Differential
cross-bridge kinetics of FHC myosin mutations R403Q and R453C in
heterozygous mouse myocardium. Am. J. Physiol. Heart Circ. Physiol.
287, H91-H99.
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Palmer BM, McConnell BK, Li GH, Seidman CE, Seidman
JG, Irving TC, Alpert NR, Maughan DW (2004) Reduced crossbridge
dependent stiffness of skinned myocardium from mice lacking cardiac
myosin binding protein-C mice. Mol. Cell. Biochem., 263, 73-80.
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Palmer BM, Noguchi T, Yang Y, Heim JR, Alpert NR,
Burgon PG, Seidman CE, Seidman JG, Maughan DW, LeWinter MM (2004)
Effect of Cardiac Myosin Binding Protein-C on mechanoenergetics
in mouse myocardium. Circ. Res. 94, 1615-1622
Frog (cytosol)
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