Publications

1. Kad, N.M., Thomson, N., Smith, D.P., Smith, D.A.M., Radford, S.E. ß2-Microglobulin and its Deamidated Variant, N17D Form Amyloid Fibrils with a Range of Morphologies in vitro. Journal of Molecular Biology, 2001, Vol. 313, No. 3, p. 559-571.
   
2. Kad, N.M., McParland V.J., Kalverda, A.P., Brown, A., Kirwin-Jones, P., Hunter, M.G., Sunde, M., Radford, S.E. Partially unfolded states of ß2-microglobulin and amyloid formation in vitro. Biochemistry, 2000, Vol.39, No.30, p.8735 –8746.
   
3. Kad, N.M. and Radford, S.E. Partial unfolding as a precursor to amyloidosis: A discussion of the occurrence, role and implications. Frontiers in Molecular Biology, No. 37, 2001. 2000, Ed. P. Lund, Oxford University Press.
   
4. Cliff, M.J., Kad, N.M., Hay, N., Lund, P.A., Webb, M.R., Burston, S.G., Clarke, A.R. A kinetic analysis of the nucleotide-induced allosteric transitions of GroEL. Journal Of Molecular Biology, 1999, Vol.293, No.3, p.667-684.
   
5. Kad, N.M., Ranson, N.A., Cliff, M.J., Clarke, A.R. Asymmetry, commitment and inhibition in the GroE ATPase cycle impose alternating functions on the two GroEL rings. Journal Of Molecular Biology, 1998, Vol.278, No.1, p.267-278.

Abstracts

1. Kad, N.M., Clarke, A.R. Conformational dynamics and cooperativity probed by the Y485W fluorescent GroEL. Protein Engineering, 1997, Vol. 10, No. SS, p.49
   
2. Kad, N.M., McParland V.J., Brown, A., Hunter, M.G., Sunde, M., Radford, S.E. De novo formation of ß2-microglobulin fibres implies preceding conformational perturbations. Protein Science, 1999, Vol. 8 No. S2.
   
3. Kad, N.M., McParland, V.J., Radford, S.E. From native state to amyloid: An investigation into fibril formation from ß2-microglobulin. Biochemistry Society Transactions, 2000. In Press

Visit Vermont Molecular Motors at UVM!

Personal Molecular Motors Group Home Page

Please send comments to webmaster.